Peptic ulcer - gastrin blood test
The gastrin blood test measures the amount of the hormone gastrin in blood.
Certain medicines may affect the results of this test. Your health care provider will tell you if you need to stop taking any medicines. Do NOT stop taking any medicine before talking to your provider.
Medicines that can increase gastrin level include stomach acid reducers, such as antacids, H2 blockers (ranitidine and cimetidine), and proton pump inhibitors (omeprazole and pantoprazole).
Drugs that can decrease gastrin level include caffeine, corticosteroids, and the blood pressure drugs deserpidine, reserpine, and rescinnamine.
When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or a slight bruise. This soon goes away.
Gastrin is the main hormone that controls the release of acid in your stomach. When there is food in the stomach, gastrin is released into the blood. As the acid level rises in your stomach and intestines, your body normally makes less gastrin.
Your provider may order this test if you have signs or symptoms of a problem linked to an abnormal amount of gastrin. This includes peptic ulcer disease.
Normal values are generally less than 100 pg/mL (48.1 pmol/L).
Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test result.
Too much gastrin can causes severe peptic ulcer disease. A higher than normal level may also be due to:
There is little risk involved with having your blood taken.Veins and arteries vary in size from one patient to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight but may include:
Bohórquez DV, Liddle RA. Gastrointestinal hormones and neurotransmitters. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 4.
Siddiqi HA, Salwen MJ, Shaikh MF, Bowne WB. Laboratory diagnosis of gastrointestinal and pancreatic disorders. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 23rd ed. St Louis, MO: Elsevier; 2017:chap 22.BACK TO TOP
Review Date: 7/16/2019
Reviewed By: Brent Wisse, MD, board certified in Metabolism/Endocrinology, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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