The total protein test measures the total amount of two classes of proteins found in the fluid portion of your blood. These are albumin and globulin.
Proteins are important parts of all cells and tissues.
A blood sample is needed. Most of the time blood is drawn from a vein located on the inside of the elbow or the back of the hand.
Many medicines can interfere with blood test results.
This test is often done to diagnose nutritional problems, kidney disease or liver disease.
If total protein is abnormal, you will need to have more tests to look for the exact cause of the problem.
The normal range is 6.0 to 8.3 grams per deciliter (g/dL) or 60 to 83 g/L.
Normal value ranges may vary slightly among different laboratories. Talk to your provider about the meaning of your specific test results.
The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens.
Higher-than-normal levels may be due to:
Lower-than-normal levels may be due to:
Total protein measurement may be increased during pregnancy.
Landry DW, Bazari H. Approach to the patient with renal disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 106.
Manary MJ, Trehan I. Protein-energy malnutrition. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 203.
Pincus MR, Abraham NZ, Bluth M. Interpreting laboratory results. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA:: Elsevier; 2022:chap 9.BACK TO TOP
Review Date: 5/1/2021
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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