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Normal pressure hydrocephalus

Hydrocephalus - occult; Hydrocephalus - idiopathic; Hydrocephalus - adult; Hydrocephalus - communicating; Dementia - hydrocephalus; NPH

Hydrocephalus is a buildup of spinal fluid inside the fluid chambers of the brain. Hydrocephalus means "water on the brain."

Normal pressure hydrocephalus (NPH) is a rise in the amount of cerebrospinal fluid (CSF) in the brain that affects brain function. However, the pressure of the fluid is usually normal.

Images

Central nervous system and peripheral nervous system
Ventricles of the brain

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Causes

There is no known cause for NPH. But the chance of developing NPH is high in someone who has had any of the following:

As CSF builds up in the brain, the fluid-filled chambers (ventricles) of the brain swell. This causes pressure on brain tissue. This can damage or destroy parts of the brain.

Symptoms

Symptoms of NPH often begin slowly. There are three main symptoms of NPH:

Diagnosis of NPH can be made if any of the above symptoms occur and NPH is suspected and testing is done.

Exams and Tests

The health care provider will perform a physical examination and ask about the symptoms. If you have NPH, the provider will likely find that your walking (gait) is not normal. You may also have memory problems.

Tests that may be done include:

Treatment

Treatment for NPH is usually surgery to place a tube called a shunt that routes the excess CSF out of the brain ventricles and into the abdomen. This is called a ventriculoperitoneal shunt.

Outlook (Prognosis)

Without treatment, symptoms often get worse and could lead to death.

Surgery improves symptoms in some people. Those with mild symptoms have the best outcome. Walking is the symptom most likely to improve.

Possible Complications

Problems that may result from NPH or its treatment include:

When to Contact a Medical Professional

Call your provider if:

Go to the emergency room or call 911 or the local emergency number if a sudden change in mental status occurs. This may mean that another disorder has developed.

Related Information

Dementia
Hydrocephalus
Cerebral spinal fluid (CSF) collection
Brain surgery
Meningitis
Subarachnoid hemorrhage
Ventriculoperitoneal shunt - discharge

References

Rosenberg GA. Brain edema and disorders of cerebrospinal fluid circulation. In: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology in Clinical Practice. 7th ed. Philadelphia, PA: Elsevier; 2016:chap 88.

Sivakumar W, Drake JM, Riva-Cambrin J. The role of third ventriculostomy in adults and children : a critical review. In: Winn HR, ed. Youmans and Winn Neurological Surgery. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 32.

Williams MA, Malm J. Diagnosis and treatment of idiopathic normal pressure hydrocephalus. Continuum (Minneap Minn). 2016; 22(2 Dementia):579-599. PMCID: PMC5390935 www.ncbi.nlm.nih.gov/pmc/articles/PMC5390935/.

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Review Date: 2/4/2020  

Reviewed By: Amit M. Shelat, DO, FACP, FAAN, Attending Neurologist and Assistant Professor of Clinical Neurology, Stony Brook University School of Medicine, Stony Brook, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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