Ibuprofen/pseudoephedrine (By mouth)
Ibuprofen (eye-bue-PROE-fen), Pseudoephedrine Hydrochloride (soo-doe-e-FED-rin hye-droe-KLOR-ide)
Relieves symptoms of cold or flu, including body aches and pains, fever, headache, or stuffy nose. This medicine contains an NSAID.
Advil Cold & Sinus, Cold & Sinus Relief, Good Neighbor Pharmacy Ibuprofen Cold & Sinus, Ibuprofen Cold & Sinus, TopCare Ibuprofen Cold & SinusThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:This medicine is not right for everyone. Do not use it if you had an allergic reaction to ibuprofen, pseudoephedrine, or similar medicines, or right before or after a heart surgery.
How to Use This Medicine:
Liquid Filled Capsule, Tablet
- Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
- It is best to take this medicine with food or milk.
- Follow the instructions on the medicine label if you are using this medicine without a prescription.
- Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid:
- Do not use this medicine if you are using or have used an MAO inhibitor (MAOI) within the past 2 weeks.
- Some medicines can affect how ibuprofen/pseudoephedrine works. Tell your doctor if you are using any of the following:
- Blood thinner
- Diuretic (water pill)
- Other cold medicine
- Other NSAIDs (including aspirin, diclofenac, naproxen)
- Steroid medicine
- Do not drink 3 or more alcoholic drinks while you are using this medicine.
Warnings While Using This Medicine:
- Tell your doctor if you are pregnant. Do not use this medicine during the later part of your pregnancy, unless your doctor tells you to.
- Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, heart disease, high blood pressure, asthma, diabetes, thyroid problems, trouble urinating, or a history of stomach problems (including heartburn) or stroke.
- This medicine may cause the following problems:
- Increased risk of heart attack, heart failure, or stroke
- Stomach bleeding
- Call your doctor if your symptoms do not improve or if they get worse.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Chest pain that may spread, coughing up blood, nausea, unusual sweating, fainting
- Numbness or weakness on one side of your body, pain in your lower leg
- Severe constipation, stomach pain, vomiting of blood, bloody or black, tarry stools
- Sudden or severe headache, problems with vision, speech, or walking
- Swelling in your hands, ankles, or feet
- Trouble breathing, cold sweat, bluish-colored skin
If you notice these less serious side effects, talk with your doctor:
- Dizziness, nervousness, trouble sleeping
If you notice other side effects that you think are caused by this medicine, tell your doctor
Last Updated: 6/2/2022