Plasminogen, Human-tvmh (By injection)
Plasminogen, Human-tvmh (plaz-MIN-oh-jen HUE-man - tvmh)
Treats plasminogen deficiency type 1 (hypoplasminogenemia).
RyplazimThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:This medicine is not right for everyone. You should not receive it if you had an allergic reaction to plasminogen.
How to Use This Medicine:
- Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. It must be given slowly, so the needle should remain in place for 10 to 30 minutes.
- A nurse or other health provider will give you this medicine.
- Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Some medicines can affect how plasminogen, human-tvmh works. Tell your doctor if you are using a blood thinner.
Warnings While Using This Medicine:
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, bleeding problems, stomach or bowel problems, lung or breathing problems, or blood clots.
- This medicine may cause the following problems:
- Bleeding problems
- Tissue sloughing or shedding, which may cause breathing problems, stomach or bowel problems, or urinating problems
- This medicine is made from donated human blood. Some human blood products have transmitted viruses (including Creutzfeldt-Jacob disease), although the risk is low because donors and blood are both tested for viruses. Talk with your doctor if you are concerned.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blood in the urine or stools, lower back or side pain
- Chest pain, trouble breathing, coughing up blood
- Cough, sore throat, voice changes
- Stomach pain, bloating, nausea, constipation
- Unusual bleeding or bruising
If you notice these less serious side effects, talk with your doctor:
- Back, arm, leg, or joint pain
- Dry mouth
- Headache, dizziness
- Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 6/2/2022